Research: Smoking Affects Drug Response

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Smoking impairs the drug response due to biological drugs used to treat inflammatory arthritis affecting the lower back, a condition called AxSpA.

The researchers tracked the treatment response to a class of specific biological drugs in 700 patients with confirmed AxSpA. Their response to treatment was assessed using recognized criteria: BASDAI and ASDAS scores. The results showed that having smoked in the past didn’t affect the response to treatment, but current smoking did. Compared with the non-smokers, current smokers responded significantly less well to their drug treatment.

Although the researchers say it is still exactly not clear on how smoking impairs response to treatment.

Source: Medical Xpress

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