An increase in the blood’s uric acid levels can lead to a metabolic disease called gout. In this disease the excess of uric acid deposits within the joints. Ineffective metabolism of body nucleic acid called purines is the leading cause of gout. Normally the purines break down into uric acid that is excreted via kidneys. However, in case of this disease the metabolic products results in:
- Over production of uric production
- Under excretion of uric acid
However, 90% of the times, the condition happens due to under excretion. The uric acid in excess amount turns into uric crystal in blood and is deposited in the joints causing inflammation and severe pain. The most susceptible joints include the big toe, knees, and ankles. However, in women gout can occur in the hands as well.
All in all, gout is a serious medical condition. If you want to know more about this painful disease then here is an easy to understand infographic for you.
Check it out!